Micronbrane Medical is advancing the field of clinical microbiology through innovative tools that enhance the sensitivity and speed of pathogen detection in liquid samples. Our proprietary Devin™ Host Depletion Filter is designed to efficiently remove host nucleated cells, enabling significant enrichment of microbial nucleic acids without the need for culture or extensive sample processing. This process improves signal-to-noise ratios in sequencing-based assays and enhances detection of low-abundance pathogens.
We have integrated this technology into our metagenomic sequencing workflow, PaRTI-Seq™ (Pathogen Real-Time Identification by Sequencing). PaRTI-Seq™ allows for unbiased, culture-independent identification of bacterial, viral, and fungal organisms within 24 hours, addressing critical limitations of conventional diagnostics. The method has been successfully validated on a diverse set of clinical and non-clinical liquid samples, demonstrating robustness in both pathogen detection and microbial community profiling.
Our platform holds particular promise in cases of sepsis, febrile illness of unknown origin, immunocompromised patients, and polymicrobial infections. By simplifying and accelerating pathogen identification, Micronbrane’s solutions support earlier clinical decision-making and antimicrobial stewardship.