Taichung Veterans General Hospital / Team of Yong-Chuan Chen

【Assisting Devices of Developmental Care for Premature Infants】
The assisting devices of developmental care for premature infants were based on neonatal development care and innovated by department of nursing in Taichung Veteran General Hospital. The assisting devices includes: nasal CPAP fixation strap, position auxiliary-nest, kangaroo blanket and newborn eye protector. Nasal CPAP fixation strap reduced ventilator used about five days on premature infants. Position auxiliary-nest improved neurodevelopment. Kangaroo blanket stable the vital signs and improve the weight gain of premature infants. Newborn eye protector improve the effect of phototherapy.

Tainan District Agricultural Research and Extension Station, Council Of Agriculture, Executive Yuan

The Application of Intelligent Agricultural Control System on Orchard

Taipei Chang Gung Mermorial Hospital, Tungs' Taichung MetroHarbor Hospital, National Taiwan Universi

Artificial intelligence for dental intraoral film mounting
This team is composed of CGMH, NTUH, Tungs' General Hospital, dental radiologists, and successfully used the intraoral image database of CGMH to train a dental film mounting AI model with high accuracy. This AI can identify clinical adult and child routines image taken in the mouth of (Periapical, Horizontal biteWing (B.W.), Vertical bitewing (V.B.W.), Occlusal), a total of 28 categories and four kinds of angles (0∘, 90∘, 180∘, 270∘) of automatic identification flip! As well as the ongoing review of the ROC invention patent, hoping to bring the industry's first partners to protect and advantage!

Taipei Madical University

Photothermal blanket
Photothermal patch
Photothermal neck guard
Photothermal mask

Taipei Medical University

MPT0G211 is a highly selective and sensitive HDAC6 inhibitor and showed significantly higher potency than ACY-1215 and ACY-241, both developed by Celgene. We also confirmed its safety without any toxicity to cardia, respiratory and center neuron system. According to our data, MPT0G211 mesylate is a potent anticancer drug, especially in multiple myeloma, showing 80-100% tumor inhibition effect when combined with current chemotherapy treatment. Moreover, it also can ameliorate cognitive impairments in Alzheimer’s disease animal studies. The well patent protected MPT0G211 has completed the majority of IND (Investigational New Drug) enabling study, only a part of chemical and manufacture control remains. The new developing drug will exclusively license to ATP BioPham, a startup derived from Taipei Medical University. ATP BioPharm now has raised an angel round and acquired tutoring and 1.5M funding supports from Silicon Valley Advantage, an accelerator in USA. MPT0G211 will be submitted to IND application to the US FDA in 2021 and proceeded to phase I clinical trial.

Taipei Medical University

Our team aims at offering the faster and safest T cell therapy for various cancers. Our core technology is a novel virus-free T cell manufacturing platform. This novel approach offers a single-step manufacturing process to obtain high purity (>90%) cancer-specific T cells in 10 days. CTA-01, the CytoArm’s lead product, has encouraging efficacies and safety profiles in in-vitro and in-vivo studies of leukemia. Other developing Armed-T cell products also demonstrated excellent in vivo therapeutic effects for solid tumors and metastatic cancers. Key patents have been filed in multiple countries and granted in Taiwan. Now, we are raising our A fund to scale up the process of CTA-01 and also looking for potential partners to co-develop and move forward to initiate IND-enabling studies.

TAIPEI MEDICAL UNIVERSITY HOSPITAL

Distal Radial fractures is one of the most common fractures, accounting up to 17~20% of fractures admitted to the emergency room. Dorsal metaphysis comminution of the distal radius and articular fracture are indicators of distal radius instability. The most popular surgery for patients with distal radial comminuted fractures is open reduction internal fixation with locking Plate and screws. We had using designed 3D printing device to assist fracture reduction and internal fixation, especially the distal radial metaphyseal comminuted fragments. Comparing the results of traditional open fixation surgeries, the use of 3D printing tools with reduction forceps can better restore the inclination of the radial articular surface, the radial height and the consistency of the joint. The printing 3D device made by biocompatible disposable materials can be aseptically prepared at high temperature without deformation, and are almost radiolucent under intraoperative X ray imaging, which will not affect the observation of fracture reduction under X ray. The combination of open internal fixation, pelvic clip and this reduction tool can provide counter force, easy to use and without resident’s assistant. Surgery can be performed with minimal invasive incision and achieve perfect reduction and internal fixation of the distal radius fracture.

Taipei Medical University Hospital

Ted-ICU AI Platform: Through reshaping the smart ICU care model, providing multi-point remote healthcare service, and AI-assisted recommendation, the Ted-ICU AI Platform can predict changes in high-risk conditions and introduce therapy and prevention at an early stage.

Taipei Medical University/ National Taiwan University

Taipei Medical University/ National Taiwan University