The exhibited product of Lukas Biomedical Inc. is Autologous Activated T Lymphocyte (ATL), as known as CIK (Cytokine Induce Killer Cells) which is T cell that has long life-span, high specificity, and regeneration ability to prolong its interaction duration in the immune system. It plays a crucial role in the anti- cancer mechanism. They are isolated from the peripheral blood of patients and generated as a cell cluster through co-culture with cytokine (such as IL-2 and CD3 antibody). This cell cluster includes several immune cells with different surface antigens. In early studies, it was found that the majority of these immune cells are CD4+ and CD8+ T lymphocytes. CD4+ helper T cells have the function of secreting cytokine to assist other immune cells, and CD8+ cytotoxic T cells have tumor-specific killing capacity. This tumor-specific killing capacity plays a critical role in the immune system to against cancer. In the latest year, CD3+CD56+ NKT cells, and CD3-CD56+ NK cells and other killer cells with cytotoxicity have also been discovered in the cell cluster.
The immunotherapy of Lukas has the following unique traits:
1. A One-time 80 ml blood collection from the patient can conduct total of six infusions. It avoids repeated blood collections from the patient.
2. Premium quality and quantity- the cell proliferation can be up to 1000 fold with 95% purity.
3. The results of phrase two and phrase three clinical trials showed that Lukas’ memory T immunotherapy could significantly prolong time to cancer recurrence.
4. This technology comes from Japan and has been on the market in South Korea. It has been manipulated on more than 10,000 patients and it has proved as safe and effective.